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Although generally considered safe in research, reported side effects may include nausea, headaches, digestive issues, fatigue, appetite changes, fluid retention, dizziness, and fluctuations in blood sugar levels

These are promising compounds, not proven medications, and anyone considering them should understand that distinction clearly

For the mTOR rescue experiment, SYK-deficient SC (shSYK-1) was treated with 5 M MHY1485 (MCE, Cat#HY-B0795) for 24 h

Authors Note: Breckas thousands of patients, zero adverse events figure is a clinical anecdote, not data

The collagenase model replicates the matrix disorganization and degenerative pathology of clinical tendinopathy more closely than transection models, strengthening the relevance of the findings to the human chronic tendinopathy condition

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