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We next describe relevant biomarkers and urge greater research interest in the potential utilization of neurotrophic agents to treat AD

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Acknowledgements This study was supported by Fondazione Cassa di Risparmio di Trieste to LM and ET and by a grant MIUR (PRIN 2010N8PBAA) to ET and is part of the collaborative consortium Italian Network on BDNF ( InBDNF )

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