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The FDA requires extensive animal testing before human trials specifically because dangerous substances generally produce detectable harm in animal models
Patients have been seriously injured and killed because of tainted versions
If a practice lacks this capacity, patients may be better served by weight management specialists or other providers with dedicated GLP-1 programs
As of August 2023, Mississippis Board of Medical Licensure banned off-label prescribing of GLP-1 agonists solely for weight loss
Its inclusion may potentially increase energy expenditure or alter fat and carbohydrate metabolism
Some patients benefit from timing medication around meals to optimize nutrient absorption and energy distribution throughout the day
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