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It is a synthetic 39-amino-acid molecule that activates three metabolic receptors GIP, GLP-1, and glucagon through a single compound
131 , e150588 (2021)
The peptide sequence has been carefully designed to optimize receptor binding affinity while maintaining stability in the body for extended periods
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The importance of TNF- can be explained by the fact that mutation of TLR-4 affects patients development of sepsis and its degree due to different responsiveness of lipopolysaccharide (LPS) (11)
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