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As age advances, mitochondrial function declines progressively, which leads to an imbalance in chondrocyte energy homeostasis, partially initiating the process of cartilage degeneration

Harvin JA, Lahat G, Correa A, Lee J, Maru D, Ajani J, Marom E, Welsh J, Bhutani MS, Walsh G, Roth J, Mehran R, Vaporciyan A, Rice D, Swisher S , Hofstetter W

Additionally, scientific literature on other GLP-1 agonists had already established the mechanistic link between this drug class and gastric motility disorders, making the risk foreseeable to any reasonable pharmaceutical manufacturer

Menstrual Migraine is tied to a woman's menstrual cycle, typically occurring before, during or after menstruation

For some people, GLP-1 RAs are part of a long-term treatment plan, especially if they continue to provide benefits like improved blood sugar control, weight loss, or cardiovascular protection

There was no restriction based on the original language of the article