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B12/MIC should be used in combination with diet and exercise to maximize results

Methylcobalamin is used to treat pernicious anemia and vitamin B12 deficiency, as well as to determine vitamin B12 absorption in the Schilling test

In trials that added it to injected insulin, basal insulin requirements fell roughly 60% to 80% while control improved. Low-blood-sugar risk therefore tracks the insulin or sulfonylurea used alongside tirzepatide more than the tirzepatide dose itself

Experts recommend taking 2.4 micrograms of vitamin B-12 each day