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Gawe-Bben, K., Czech, K

it competitively binds to cellular receptors, blocking the body's natural active B6 and potentially inducing a functional deficiency that leads to peripheral neuropathy (nerve tingling and pain)
A 2020 study of "wellness" B12 injections in non-deficient adults found no improvement in energy, mood, or cognitive function versus placebo at 4 weeks (Wolffenbuttel et al., Nutrients , 2020)

Epub 2021 Jul 27

Ma H, Liu S, Li S, Xia Y
These observations suggest that besides modulating HSCs homeostasis, GPX4 may also have an important role in regulating monocyte and macrophage functions
