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However, as these drugs continue to rise in popularity and demand, we are still in the early stages of fully understanding what the primary applications may be for off-label use

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456 Similarly, emodin has been shown to reduce inflammatory mediator levels, 457 inhibit the apoptosis of intestinal epithelial cells

The treatment is generally well-tolerated under medical supervision, though some individuals may experience mild, transient gastrointestinal effects as the body adapts