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Benefits will vary based on ones' lifestyle therefore the best guage for frequency will be how you feel.

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Many patients with partial tears or chronic tendinopathy experience significant improvement within 8-12 weeks

A Cochrane review comparing oral and intramuscular B12 found comparable effects on blood levels, and the same principle of good absorption applies to the subcutaneous route

It has two functions: 1) to produce enzymes that help in digestion of food and, 2) to produce hormones such as insulin