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19 Nevertheless, in 2017, the FDA added an warning to Januvia's package insert that advised prescribers to weigh the risks and benefits of sitagliptin in patients at risk for HF before initiating therapy

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Further, Xavier noted that she and her colleagues did not assess possible psychiatric side effects with these drugs in the studies they reviewed, so they could not say that these GLP-1 receptor agonists were completely safe in their own findings

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