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Biphasic half-life [edit] Many drugs show a biphasic decline in plasma concentration after a dose: a steep distribution phase as drug leaves the central compartment for tissues ( phase), followed by a shallower elimination phase as drug is cleared ( phase)

Many patients report reduced appetite and fewer cravings around this time

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Some patients experience nausea, constipation, reflux, fatigue, appetite suppression, diarrhea, abdominal discomfort, dizziness, or difficulty eating enough protein