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Cohort characteristics and treatment effects were sourced from PIONEER 2 and 4 for the comparisons of oral semaglutide 14 mg versus empagliflozin 25 mg and liraglutide 1.8 mg, respectively, and PIONEER 3 for oral semaglutide 7 and 14 mg versus sitagliptin 100 mg

Derosa, G

In summary, tirzepatide achieved more pronounced HbA1c reductions with a lower incidence of hypoglycemia at week 52 compared to insulin glargine

Ras-raf-mek-dependent oxidative cell death involving voltage-dependent anion channels

Ethics declarations Authors relationships and activities MT is a member of the scientific advisory board of ERX Pharmaceuticals, Cambridge, MA