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Heating can degrade peptides, so working at room temperature is advisable

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Kojima, Masayasu, Hosoda, Hiroshi, Date, Yasuhiko, Nakazato, Mitsunobu, Matsuo, Hiroaki, and Kangawa, Ken

doi: 10.1016/0022-510X(94)00283-T 68

In addition, we have found that early knee motion, most commonly using a stationary bike, is very beneficial to help the healing MCL collagen fibers line up correctly and thicker so that they heal well

[7] [4] If you experience any unexpected or concerning symptoms following injection, err on the side of caution and seek medical advice promptly