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USA 115 , 92769281 (2018)
These favorable effects may contribute to the observed survival benefits in patients with type 2 diabetes and concomitant AKD
Indirectly, weight loss may lessen mechanical friction in flexural sites, reduce moisture and maceration, and dampen the obesity-related state of low-grade systemic inflammation
Cait and colleagues note that activation of Podxl may assist with decreasing the permeability of the BBB in diseases such as multiple sclerosis or stroke, whereas increasing the permeability may help with temporarily opening the BBB to allow therapeutics to reach brain tissue
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