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These compounds undergo activation to toxic metabolites by numerous reactions, including glucuronidation by UGTs, acetylation by NATs, sulfonation by SULTs, and conjugation with amino acids by aminoacyltRNAsynthetase
Upstream of this methyl donation, 5-methyltetrahydrofolate (5-MTHF) passes a methyl group to B12 to form methylcobalamin, which in turn converts homocysteine into methionine
[PMID: 26463132] PubMed record related to this compound for laboratory literature review
Sublingual vitamin B12 compared to intramuscular injection in patients with type 2 diabetes treated with metformin: a randomised trial
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