tirzepatide vision loss changes NEJM Editorial Fellow Katerina Lin, MD, unpacks the science behind a study on Ozempic and vision loss: GLP-1

Luminescence 29 , 722727 (2014)

What about heart and kidney protection

Statistics and reproducibility The phase 2 clinical trial was powered to show a difference in proportions of 28% on primary endpoint MASH resolution and no worsening of fibrosis between once-daily semaglutide 0.4 mg (assumed 45% response) and placebo (assumed 17% response)

doi:10.1080/13543784.2020.1705277 Muller TD, Bluher M, Tschop MH, DiMarchi RD

Eden advertises compounded semaglutide at $99 and tirzepatide at $199, plus a required $39 introductory and $99 ongoing membership

Probiotics: Semaglutide alters gut motility, which can disrupt the microbiome