Recombinant Human TNF-related Weak Inducer of Apoptosis Receptor/TNFRSF12A (Human TWEAK Receptor/TNFRSF12A)_C230507 Other growth factors potent growth factor capable of

potent growth factor capable of inducing cell proliferation

coli-derived human MIC-B protein

shares 85% amino acid identity with MICB

sharing 27% aa sequence homology

The biologically active determined by a chemotaxis bioassay using human monocytes is in a concentration range of 10-100 ng/mL

Recombinant Human TNF-related Weak Inducer of Apoptosis Receptor/TNFRSF12A (Human TWEAK Receptor/TNFRSF12A)_C230507 Other growth factors potent growth factor capable ofTWEAKR belongs to the TNF family of transmembrane proteins, and contains a cytoplasmic "death domain", which can activate a cell's apoptotic machinery. It is expressed in the spleen, thymus, peripheral blood lymphocytes, colon, and small intestine. Signal transduction by TWEAKR can be activated by either membrane anchored or soluble TWEAK. Recombinant Human soluble TWEAKR is a 53 amino acid polypeptide (5. 6 kDa) comprising the entire extracellular