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4), which did not withstand the adjustment for weight loss (Supplementary Table 2)

Plasma levels of endogenous and stable isotopelabeled l-carnitine, BB, and TMAO were determined by stable isotope dilution liquid chromatographytandem mass spectrometry (LC-MS/MS) in positive multiple reaction monitoring (MRM) mode as previously described (6) using a Shimadzu 8050 triple quadrupole mass spectrometer with ultra-HPLC interface

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Identification of the peptide and receptors, however, does not by itself substantiate a functional relevance, but evidence for a physiological role of these receptor populations emerged 13 years later and will be discussed here

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