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Wharton S, Calanna S, Davies M, Dicker D, Goldman B, Lingvay I, Mosenzon O, Rubino DM, Thomsen M, Wadden TA, Pedersen SD

IGF-1 and its analogs are prohibited at all times under the WADA Code due to their anabolic and regenerative effects. World Anti-Doping Agency (WADA) Disclaimer This article is for educational and informational purposes only

3.1.3 DON DON (6-diazo-5-oxo-l-norleucine), a glutamine analog, irreversibly inhibits various glutamine utilization enzymes, such as glutaminase and glutamine synthetase, by forming covalent bonds with nucleophilic residues on the active site of the enzyme (Rajagopalan and DeBerardinis, 2011

Its extended half-life makes it a powerful research tool but also means its effects persist much longer than natural IGF-1

If it can demonstrate superior MACE reduction, it will shift to first line in cardiovascular prevention in obese patients

But for others, theres a simpler, more affordable path