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A pivotal 2021 clinical trial of semaglutide showed that participants lost an average of 15% of their body weight over 68 weeks, compared to just 2% in the placebo group

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Black stools related to gastrointestinal bleeding tend to occur more frequently in older adults, particularly those taking medications that increase bleeding risk

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Rofeal et al., 2022), as well as fungi (Poznanski et al., 2023