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Clinical studies, including the STEP trial extensions, have demonstrated that many patients experience gradual weight increase after stopping treatment

Patkowska-Sokoa, B

This means the weight loss that felt easy at first becomes harder over time, because your body is burning fewer calories at baseline

[3] Walker, E., Lo, K., Tham, S., Pahl, M., Lomiwes, D., Cooney, J., Wohlers, M., & Gopal, P

Sangeetha MK, Balaji Raghavendran HR, Gayathri V, Vasanthi HR (2011) Tinospora cordifolia attenuates oxidative stress and distorted carbohydrate metabolism in experimentally induced type 2 diabetes in rats

Appraising the role of astrocytes as suppliers of neuronal glutathione precursors