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Why it matters: Widespread shortages of GLP-1 drugs such as Novo Nordisk's Ozempic and Wegovy and Eli Lilly's Zepbound and Mounjaro have triggered a rush of companies seeking to exploit a loophole that allows them to sell compounded versions of the injections
People with diabetes, particularly severe diabetes, tend to lose less weight with GLP-1s than people without diabetes, so microdosing is less likely to be as effective, though their dose should only be increased as they tolerate it. George said that in her professional opinion, microdosing is a potential option for patients with smaller amounts of weight to lose or as a bridge to start, or wean off, regular GLP-1 medications
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The compounded dosage calculator helps you plan doses with vial formulations
There is currently no evidence that semaglutide becomes toxic or poisonous after it expires
All MS and MS/MS data for protein samples were processed with the Proteome Discoverer software (Thermo Scientific, version 2.1) coupled to an in-house Mascot search engine (Matrix Science, version 2.5.1)
