Final research-target dose 2.4 mg + 2.4 mg weekly Titration length ~16 weeks Trial duration 68 weeks (REDEFINE 1 / REDEFINE 2) Route Subcutaneous, once weekly Compound Delivery: 2.4 mg / 2.4 mg Maintenance Pre-blended vials simplify weekly administration to a single injection but lock the ratio at 1:1
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efficacy, safety and toxicity
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The choice of neurogenic markers in this study was based on their established roles in neural development and plasticity
As an antioxidant, glutathione helps to reduce oxidative damage caused by free radicals, which can lead to fatigue