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The weight change at one year post-discontinuation was small, but depended heavily on the individual and may partly reflect the fact that many patients resumed or transitioned to other weight-management therapies rather than remaining untreated

Elevated expression of ER stress markers, including GRP78, ATF-6, X-box binding protein-1, C/EBP homologous protein (CHOP), and phospho-Jun N-terminal kinase (p-JNK), was evident in the hippocampal CA1 of diabetic rats, 68 which may ultimately affect synaptic plasticity

Edelman M, et al

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Guillotine (open) technique used for contaminated or ischemic wounds requiring staged closure

Nausea is common during the first few weeks and typically diminishes over time