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28 Foundational studies of lipid autoxidation chemistry have been essential in establishing this framework and in showing that radical-trapping antioxidants act by terminating the chain-propagation phase of lipid peroxidation, 29,30 thereby defining the kinetic control points that govern ferroptotic escalation

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While the expression of DNMT3B, DNMT3L, and TET1 is barely detectable in SCD erythroblasts, the expression of DNMT1, DNMT3A, TET2 or TET3 was not significantly changed at the mRNA or protein level after DMF treatment (Supplementary Fig