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Advancements in next-generation sequencing and protein expression profiling have demonstrated that the renal targets of thiazides, i.e., Na + Cl cotransporter (NCC, encoded by SLC12A3 ) and that of bumetanide/furosemide, i.e., Na + K + 2Cl cotransporter-2 (NKCC2, encoded by SLC12A1 ) are expressed in different tissues and cells, albeit at lower levels (Di Fulvio and Alvarez-Leefmans, 2009)
Patients can still get coverage if they have a diagnosis of Type 2 diabetes, cardiovascular disease or sleep apnea, but not if they have obesity only or for weight loss generally
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Final thoughts Final thoughts The development of any therapeutic requires decades of foundational basic biology research, coupled with concerted efforts to drive those fundamental insights and translate them into medicines
The Hospira bacteriostatic water for injection contains 0.9% benzyl alcohol, making it suitable for multi-dose use
PMID 17186181
