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This bidirectional relationship provides potential avenues for the prevention of accelerated biological aging and the identification of therapeutic targets
Xing, X
Mitchell et al.[6] measured the level of GSH depletion in the liver (of mice), and the amount of covalent binding of radiolabeled APAP metabolites (later identified as NAPQI) in the liver after a wide range of doses of APAP
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PMID 18245139
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