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Semaglutide Research Applications GLP-1 receptor pharmacology in pancreatic beta-cell lines and HEK293 cells expressing human GLP-1R, where semaglutide serves as the standard long-acting agonist for characterizing binding affinity, EC values, and downstream cAMP signaling

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The LR3 modification increases its half-life, making it more potent and beneficial for muscle regeneration and tissue repair

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