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Second, EtOH exposure, especially when chronic, reduces the antioxidant capacity of the liver and blood, as reflected by decreased levels of antioxidants (e.g

Exogenously administered GSH protects against oxidative damage in cultured human RPE 17 , while GSH depletion was shown to cause cell death 18

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Current reliance on preclinical evidence underscores the urgent need for rigorous clinical trials