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Bioanalysis 6 , 23912402 (2014)

10.1016/j.ejphar.2019.01.030 106 SeverM.KlicekR.RadicB.BrcicL.ZoricicI.DrmicD.et al (2009)

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Obesity has a strong biological basis involving hormonal signaling, genetic predisposition, and metabolic setpoints that resist change

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The anti-aging and skin rejuvenation research protocols from clinical literature use 1mg daily as a starting point, with 2mg daily for accelerated protocols or those specifically targeting tissue repair during active fat loss