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doi: 10.1165/rcmb.2017-0344ED 42 KrausgruberTRedlABarrecaDDobererKRomanovskaiaDDobnikarLet al
2013 Nov-Dec;27(6):565-9
The first GLP analog, Byetta, was approved in 2005, and since then, many diabetics have used these medications for life
Whilst mild to moderate liver disease may not require dose adjustments, there is limited clinical experience with severe hepatic dysfunction
Unlike naturally occurring peptide hormones, which are rapidly broken down by enzymes within minutes, retatrutide contains several engineered modifications that substantially extend its biological half-life
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