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Participants had a mean baseline starting weight of 226-231 lbs
GLP-1 A
Body weight was measured daily to monitor weight loss, and the glucose-lowering efficacy of the treatments was determined after 26 days by measuring hyperglycaemia, hyperinsulinaemia and insulin resistance (see ESM Methods: Metabolic tests)
Dosing and Escalation Protocols Both peptides use weekly subcutaneous injection and both require careful dose escalation to minimize side effects
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