A diferencia de los GLP1-RA, se ha observado en la evidencia clnica que los IDPP-4 no tienen beneficios cardiovasculares en pacientes con DM2 a pesar de contribuir en el control glucmico, por lo que no cumplen con los nuevos lineamientos en el tratamiento de la DM2, donde se busca reducir la incidencia de complicaciones ms all del control glucmico 58
Tesamorelin is the most clinically validated option for visceral fat reduction, with FDA approval and robust trial data backing it
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Protein intake is especially important when using GLP-1 medications because weight loss can include muscle loss if protein intake is too low