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AR is mostly triggered by inhalations allergens, including fungal spores, pollen particles, and dust mites, most of which can be clearly identified by allergen detection techniques [3]
In Alzheimers disease, NLRP3 inflammasome has emerged as a pathological component participating in the impaired removal of amyloid- by microglia (Lonnemann et al., 2020)
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The cardiovascular protective mechanisms of GLP-1 receptor agonists are thought to include: Improved glycaemic control , reducing endothelial dysfunction associated with hyperglycaemia Weight reduction , decreasing metabolic stress and inflammation Blood pressure lowering , potentially through effects on fluid balance and vascular function Favourable lipid profile changes , including modest reductions in LDL cholesterol and triglycerides Anti-inflammatory effects , reducing systemic markers of inflammation such as C-reactive protein Regulatory bodies including the MHRA and EMA have not identified thrombotic events as a specific safety concern with GLP-1 receptor agonists
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