doi: 10.1016/S0002-9343(98)00168-5 340 RimesKALievesleyKChalderT
Kwan, B
Liposuction permanently removes fat cells from treated areas, but untreated areas can still expand if your weight increases
Based on early human studies and animal research, GLP-1 agonists may affect: Reward-related eating behaviours by potentially modulating dopamine signalling in brain reward circuits Food cravings and hedonic eating (eating for pleasure rather than hunger) Impulsivity around food , possibly reducing the compulsive aspects of eating Satiety signalling , enhancing the feeling of fullness after meals Some patients using GLP-1 medications for diabetes or weight management report not just reduced appetite but also diminished preoccupation with food, fewer intrusive thoughts about eating, and reduced cravings for specific foods, particularly those high in fat and sugar
The strongest data remain in weight loss and cardiometabolic outcomes, but arthritis-specific benefits are being actively studied, so excited to see where this goes
However, we should highlight the translatability of most of these methods, which are currently being used in clinical research