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Janez A, Muzurovic E, Stoian AP, et al

Other mechanisms underlying the effects of GLP-1 RAs on exercise capacity include improvements in myocardial energetics, enhanced endothelial function, reductions in systemic inflammation and oxidative stress and modulation of skeletal muscle metabolism

I suspect this is from the glucagon agonism of the drug as glucagon stimulates the formation of extra bile acids/bile salts in the liver which can be very irritating to the intestinal lining causing diarrhea

Environmental and molecular mutagenesis , 58 (2), 6071

Research is still working to fully understand the role incretins play in overall health

5-HTP, a precursor to serotonin, supports enteric nervous system function