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Liraglutide does not alter behavioural markers of ALS in SOD1 G93A transgenic mice Due to the tolerated higher 75 nmol/kg liraglutide dose and the larger effect on blood glucose levels, we dosed SOD1 G93A transgenic mice with vehicle, 25 nmol/kg or 75 nmol/kg liraglutide from 25 to 90 days of age

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N Engl J Med 316:971977

Higher systemic exposure of dapagliflozin in patients with type 2 diabetes mellitus with renal impairment did not result in a correspondingly higher 24-hour urinary glucose excretion

doi: 10.1039/C8CC02669F 22 LanttoR.PuolanneE.KruusK

As a dual GIP/GLP-1 receptor agonist, tirzepatide works through two pathways rather than one, which clinical trials have shown produces greater average weight loss compared to semaglutide alone