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Contact your GP or NHS 111 within 72 hours if you develop: A painful rash with blisters on one side of your body Suspected shingles symptoms , particularly if you're over 50 or have a weakened immune system Rash on your face , especially near the eye, as this requires urgent specialist assessment Severe pain that interferes with daily activities or sleep Seek same-day medical attention or attend A&E if: Shingles affects the eye or surrounding area (ophthalmic shingles) this can threaten vision and requires immediate ophthalmology review You have a weakened immune system from any cause and develop suspected shingles The rash becomes widespread or affects multiple body areas You develop severe headache, neck stiffness, confusion, or sensitivity to light potential signs of neurological complications The affected area shows signs of bacterial infection (increasing redness, warmth, swelling, or pus) You have ear pain and facial weakness (possible Ramsay Hunt syndrome) Regarding your Wegovy treatment: Continue taking Wegovy unless specifically advised otherwise by your healthcare provider Inform your prescriber that you've developed shingles, particularly if you experience significant illness or reduced oral intake Maintain adequate hydration and nutrition during shingles treatment, as this supports both recovery and the effectiveness of your weight management programme Antiviral medications (such as aciclovir, valaciclovir, or famciclovir) are the mainstay of shingles treatment

NICE Technology Appraisals are mandated for NHS funding, and NHS organisations must normally fund treatments recommended by NICE within three months of guidance publication

B12 is a vitamin that is essential for metabolic and energy processes in the body

Taspoglutide prevents apoptosis in vitro , promotes -cell proliferation, and exerts multiple protective effects of -cell in Zucker Diabetic Fatty rats [20]

Additional animal models reported improved healing in ligament injuries, muscle crush injuries, quadriceps transections, tendon-to-bone healing environments, and corticosteroid-impaired healing models

Researchers believe the glucagon receptor activation may play a role here