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Because methylation impacts so many systems, MTHFR gene mutation symptoms can vary widely
10.1111/j.1365-2265.2011.04042.x 144 RotondiM.CoperchiniF.PignattiP.MagriF.ChiovatoL
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(1983a)
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Acetylcholine (ACh) released from neurons activates muscarinic ACh receptors (MRs) on ECs, increasing nitric oxide (NO) production, EC hyperpolarization, and consequently, elevated CBF [92]
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