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Higher body fat percentage slightly increases BAC since fat tissue contains less water than muscle
[81] However, it is no longer the reference method due to the high measurement uncertainty of vitamin B 12
While safety was established, efficacy for weight loss did not meet clinical trial success criteria
Yet the consequences are unknown Bioavailability: there are four specific metabolic steps necessary to convert cyanocobalamin into one of the coenzyme forms, which is a clear metabolic disadvantage (3) Utilisation problems: certain hereditary diseases, as well as metabolic disorders, prevent the conversion of cyanocoalamin into the active B12 forms (4) Steals methyl groups: cyanocobalamin requires a methyl group to convert into methylcobalamin, which it takes from the important amino acid S-adenosylmethionine (SAM)
Even when injected systemically into abdominal fat, the peptide appears to concentrate at injury sites
As such, a person with B12 deficiency may have difficulty walking and balancing (2)
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