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Research applications include: Wound Healing and Collagen Biosynthesis induction of ECM gene expression and fibroblast proliferation (Pickart et al., 2015)

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When used as monotherapy, tirzepatide has a very low risk of causing clinically significant hypoglycemia (less than 0.6% incidence), similar to placebo, due to its glucose-dependent mechanism of action that limits insulin secretion when blood sugar approaches normal levels

Or tirzepatide constipation might ease up when switching to semaglutide, which carries its own GI profile

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