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251 The results of immunoblotting and immunocytochemistry of central nervous system tissues suggested elevated p53 protein levels and the abnormal localization of p53 in ALS patients

Importantly, tumor take was remarkably reduced with RETA ( N = 4/8, 50%) compared to Veh ( N = 7/7, 100%) (Fig

Optimal results require minimum 16-week protocols, ideally extended to 6+ months for comprehensive evaluation

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Rapid return of symptoms may indicate need for longer treatment duration or different approaches