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It is administered intravenously or intramuscularly by a healthcare professional, with dosing tailored to the individual patients needs and clinical response

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XOI has had favorable treatment effects on experimental small animal models of hypertension, renal disease progression, atherosclerosis, and NASH [16, 19, 20], though net effects of XOI-based urate-lowering therapy remain unclear in adult humans with these conditions [21]

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When water enters the skin, it hydrates cells as well as the extracellular matrix, which can reduce the appearance of fine lines and wrinkles

32 (Suppl 1), 99118 (2016)