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The oxidative stress defense enzymes heme oxygenase-1 (HO)-1 and glutathione-S-pi transferase (GST-pi) were regulated by bilberry anthocyanins (1 mg/mL) in retinal pigment epithelial cells that were pre-incubated with anthocyanin extract prior to H 2 O 2 exposure

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Maintaining an adequate GSH redox status and 25-hydroxy-vitamin D levels will have the potential to reduce oxidative stress, enhance immunity and diminish the adverse clinical consequences of COVID-19 especially in African American communities having glucose-6-phosphate dehydrogenase deficiency, enzyme necessary to prevent GSH exhaustion and depletion (Jain and Parsanathan, 2020

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