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The short-chain amino acids serve as the building blocks of proteins and key signaling molecules in the body, helping regulate several functions, including immune response, muscle protein synthesis and hormonal cycles
NNMT inhibition with 5-Amino-1MQ reduced white adipose tissue mass by ~35% in diet-induced obese mouse models without suppressing food intake, suggesting energy expenditure modulation
This binding makes the toxic compound more water soluble and assists in the bodys efforts in eliminating the toxin (4)
PMC 2992378
doi: 10.1111/dom.12291 225 ZhaoHWeiRWangLTianQTaoMKeJet al
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