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It stimulates the GLP-1 receptor in pancreatic ?-cells to enhance glucose-dependent insulin secretion, suppresses pancreatic ?-cell glucagon secretion, and directly acts on appetite-regulating centers in the brain

Curcumin alleviates aristolochic acid nephropathy based on SIRT1/Nrf2/HO-1 signaling pathway

This is actually a gentler transition than stopping a short-acting drug

(PubMed) Moses EK, Johnson MP, Tommerdal L, et al

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Pearson-Leary J, McNay EC (2016) Novel roles for the insulin-regulated glucose transporter-4 in hippocampally dependent memory