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Oral forms require strict dosing instructions to make sure that enough gets into the body
Studies show GLP-1 agonists like Ozempic can affect the gallbladder
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Zamboni M, et al
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27 Importantly, GLP-1 action is short-lived, with a half-life of just 12 minutes in the bloodstream under normal physiological conditions, after which it is broken down by the enzyme dipeptidyl peptidase IV (DPP-4), resulting in a loss of its biological activity
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