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The brain is particularly vulnerable to oxidative stress due to its high oxygen consumption, abundant polyunsaturated fatty acids, and relatively modest antioxidant defenses compared to other organs [1][2][48]
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The high abundance and rapid and steady increase of glutathione observed in this study indicate that oxidized GSSG can serve as the oxidant for class III peroxidases for ROS production
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Neither compound affects FSH, LH, PRL, or TSH, providing genuine selectivity for the GH axis
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