Castelletto V et al
Gastrointestinal adverse effects, including eructation, are well-documented with GLP-1 receptor agonist therapies in the MHRA/EMC SmPC for Mounjaro
It is being developed by Eli Lilly and Company and is currently undergoing Phase 3 clinical trials, which are necessary to establish long-term safety, efficacy, and optimal dosing in larger, more diverse populations before a regulatory submission can be made
The difference comes down to your goals and how your body responds
Complex carbohydrates with a low glycaemic index are preferable, including wholegrain bread, brown rice, oats, quinoa, sweet potatoes, pulses, and whole fruits
Initially, the agonist properties of these ligands were compared to GLP-1 in a cAMP-sensitive luciferase reporter gene assay (CRE-luc) and revealed potency as reported previously (Fig