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32 Dabrafenib also has been associated with development of keratoacanthomas or well-differentiated cutaneous squamous cell carcinoma in 6% to 26% of patients

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Any discrepancies in the extracted data were resolved by consensus through discussion between the two reviewers or resolved by a third researcher (XM)

In NRF2 active cells, this reaction produces toxic and wasteful metabolites, consequently leading to the epigenetic silencing of CDO1 in human non-small cell lung cancer to alleviate this detrimental metabolism